About this historical patient account: The information below describes reported observations from one case. It does not establish treatment efficacy, safety, a causal relationship or an expected outcome. Outcomes vary, and reported improvement does not demonstrate cure. Do not change prescribed medicines or delay established care based on this account.

Intervention context: This account does not establish that the cell, growth-factor or other biological interventions described are approved or effective for this diagnosis. Some may be investigational. A qualified specialist should explain the current evidence, regulatory status, alternatives, uncertainties and risks before any treatment decision.

Case Study: Spinal Cord Reconstruction Surgery for Complete Spinal Cord Injury

Patient Information:

• Name: Tamer Saied Ahemed
• Date of Birth: January 1, 1980
• Gender: Male
• Country: Egypt

Admission History:
A 34-year-old male presented to Beijing Puhua International Hospital with a history of lower limb mobility disorder following a car accident more than three months prior.

Diagnosis:
Complete spinal cord injury (SCI) at D5-6 level, secondary paraplegia, left hemo-thorax, right pneumothorax, comminuted fracture of the left tibia, and minimal abdominal fluid collection with fractured ribs. The injury was confirmed by MRI on July 15, 2012.

Treatment:
The patient underwent Spinal Cord Reconstruction Surgery and Neural Growth Factor Therapy in two stages:

1. First Stage (October 17, 2012): Intra-spinal exploration via a posteromedial approach through the original incision was performed. Nerve cell activation with lesion biopsy was also conducted.

2. Second Stage (July-August 2013): Four courses of Neural Growth Factor Therapy were administered via lumbar puncture on July 15, 19, 22, and 26, respectively.

Medical Condition before Treatment:

• Muscle strength: 5/5 in upper limbs, 0/5 in lower limbs
• Deep-tendon reflex symmetrically absent in legs
• Sensation below T4 level absent
• Both feet congested and edematous with multiple bedsores on the lower limbs

Postoperative Course:

One month after surgery (November 2012):

• Patient's condition improved significantly
• Vital signs stable, clear speech, and good spirits
• Limb movement started to improve
• Sensory level showed remarkable improvement from T4 to T6
• Incision healing well

Nine months after surgery (July 2013):

• Sensory level further improved to T6
• Muscle tone of lower limbs improved
• Deep sensation felt in knees and ankles while standing
• Muscular contractions noted in the left calf

Patient Satisfaction and Follow-up:
Tamer expressed satisfaction with his initial response to the Spinal Cord Reconstruction Surgery and Neural Growth Factor Therapy. Close monitoring of his physical condition will continue at Beijing Puhua International Hospital.

Conclusion:
This case describes reported changes in sensation, muscle tone and movement after several interventions. It cannot establish treatment efficacy or predict outcomes for other people with complete spinal cord injury.

About this historical patient account: The information below describes reported observations from one case. It does not establish treatment efficacy, safety, a causal relationship or an expected outcome. Outcomes vary, and reported improvement does not demonstrate cure. Do not change prescribed medicines or delay established care based on this account.

Intervention context: This account does not establish that the cell, growth-factor or other biological interventions described are approved or effective for this diagnosis. Some may be investigational. A qualified specialist should explain the current evidence, regulatory status, alternatives, uncertainties and risks before any treatment decision.

Case Study: Spinal Cord Reconstruction Surgery for Spinal Cord Injury

Patient Information:

• Name: Christopher Paul
• Diagnosis: Spinal Cord Injury (SCI)
• Date of Birth: January 14, 1983
• Gender: Male
• Country of Origin: United Kingdom

Medical History and Admission:

Christopher Paul, a 21-year-old male, was admitted to Beijing Puhua International Hospital with a three-year history of movement disorder in his right leg following a previous injury.

Preoperative Evaluation:

• Pain sensation below the right groin was absent (<1cm) and reduced (<3cm) on the left side.
• Muscular tension was normal in all four limbs.
• Upper limb muscle strength was normal (5/5), while the right lower limb had abnormal muscle strength (0/5).
• Ankle clonus test was negative, but pathological signs were positive on the right side.
• An incisional scar was present in the middle of the lower back.

Treatment and Intervention:

After admission, Christopher underwent spinal cord injury exploration via a posterior midline approach. Intraoperative management included fluid infusion to prevent dehydration, meticulous hemostasis, infection prophylaxis, and administration of cerebral nutrients. In conjunction with neurosurgical intervention, Neural Growth Factor Therapy was administered via lumbar puncture.

Postoperative Course and Outcome:

Following 19 days of inpatient treatment, including surgery and rehabilitation training, Christopher reported significant improvement in his mid-body and upper limb strength. The surgical wounds healed Class-A, with stitches removed successfully. Christopher expressed extreme satisfaction with the initial therapeutic response.

Conclusion:
This case describes reported changes following surgery, Neural Growth Factor Therapy and rehabilitation. It cannot establish the efficacy of any one intervention or predict results for other patients.

About this historical patient account: The information below describes reported observations from one case. It does not establish treatment efficacy, safety, a causal relationship or an expected outcome. Outcomes vary, and reported improvement does not demonstrate cure. Do not change prescribed medicines or delay established care based on this account.

About this historical patient account: The information below describes reported observations from one case. It does not establish treatment efficacy, safety, a causal relationship or an expected outcome. Outcomes vary, and reported improvement does not demonstrate cure. Do not change prescribed medicines or delay established care based on this account.

Intervention context: This account does not establish that the cell, growth-factor or other biological interventions described are approved or effective for this diagnosis. Some may be investigational. A qualified specialist should explain the current evidence, regulatory status, alternatives, uncertainties and risks before any treatment decision.

Patient Information

• Name: Cesar Sebastiao
• Diagnosis: Spinal Cord Injury (SCI)
• Date of Birth: January 1, 1978
• Gender: Male
• Country of Origin: Brazil

Treatment Course
Cesar sustained a severe SCI following an accidental three-story fall. Initial CT scan revealed a significant fracture at vertebra T-11. After anatomical fixation surgery, Cesar sought further improvement and traveled to Beijing Puhua International Hospital for spinal cord reconstruction.

Medical History

• Pre-Operative: Cesar was paraplegic with complete loss of lower extremity motor function, confined to a wheelchair. He experienced considerable inconvenience in daily life activities and faced professional challenges as a dentist.
• Post-Operative (21-day treatment course): Spinal Cord Reconstruction Surgery combined with Neural Growth Factor Therapy, Traditional Chinese Medicine, and Rehabilitation Therapy.

Outcome
Cesar's condition demonstrated marked improvement following the treatment regimen. Through intensive rehabilitation exercises, he regained the ability to stand and walk forward with assistance from a therapist and orthotics—a feat previously unattainable. Upon discharge, Cesar expressed optimism about returning to a relatively normal personal and professional life as a dentist in Brazil.

Conclusion
This case reports changes after surgery and supportive care. It cannot establish the contribution of each intervention, treatment efficacy or expected outcomes for other patients.

Disclaimer: Individual results may vary. This case study is intended for educational purposes only.