About this historical patient account: The information below describes reported observations from one case. It does not establish treatment efficacy, safety, a causal relationship or an expected outcome. Outcomes vary, and reported improvement does not demonstrate cure. Do not change prescribed medicines or delay established care based on this account.

Intervention context: This account does not establish that the cell, growth-factor or other biological interventions described are approved or effective for this diagnosis. Some may be investigational. A qualified specialist should explain the current evidence, regulatory status, alternatives, uncertainties and risks before any treatment decision.

Patient Information:

• Name: Alexey Nechaev
• Diagnosis: Progressive Muscular Dystrophy (Duchenne's)
• Date of Birth (D.O.B): January 3, 2002
• Gender: Male
• Country: Russia

Treatment: Nerve Growth Factor Therapy + Traditional Chinese Medicine (TCM) + Rehabilitation Therapy (Physical & Occupational Therapy)

Medical History:
Alexey, a 9-year-old boy from Russia, was admitted to Puhua International Hospital due to progressive weakness in all four limbs for seven years. He started falling while walking at age 2 and developed a "duck gait" at age 3. At age 5, he was diagnosed with Duchenne Muscular Dystrophy via genetic testing. He received medication and regular rehabilitation training.

Medical Condition Before Nerve Growth Factor Therapy:

• Alert, normal emotion, cognition, and speech
• Poor muscle power in trunk and limbs; felt helpless with daily movements
• Muscular atrophy in all four limbs
• Balance and flexibility of movement impaired
• Walked alone for approximately 20 steps with difficulty; abdomen and pelvis had excessive anterior tilt; soles of feet did not touch the ground properly
• Had difficulty getting up from a chair or bed after prolonged sitting

Nerve Growth Factor Therapy for Muscular Dystrophy:

• Injections of neural nerve growth factors
• Traditional Chinese Medicine (TCM)
• Rehabilitation therapy (physical & occupational therapy)

Medical Condition After Nerve Growth Factor Therapy:

• Improvement noted from first injection:
  • Quickened transition from sitting to standing
  • Improved muscle strength and volume; gained approximately 3 kg in weight
  • Reduced excessive anterior tilt of abdomen and pelvis while walking
  • Easier standing up and stepping forward compared to prior condition
  • Left foot sole completely touched ground; right foot sole mostly touched ground during gait
• Now able to:
  • Go to the toilet independently
  • Walk approximately 50 meters
  • Throw ball horizontally for 2 meters in rehabilitation training
  • Complete more than 20 minutes of rehabilitation training without obvious fatigue